The packed bed columns and coiled loop reactors have been designed to make safe working and easy handling. The columns can be filled with different solid catalysts, and furthermore it provides some advantage, such as easy usage, storage, transport until the catalyst deactivates. The benefits of application of coiled loop reactors have demonstrated many times, for example: shorter reaction time, better heat transfer, higher and reproducible yield. These columns and coiled loop reactors can be made from stainless steel, PEEK, PTFE or composite materials due the user requirements. Our columns and coiled loop reactors can be equipped with Swagelok or/and VICI fittings; therefore, it can be compatible with flow reactor systems.